The Best Bed Bug Sprays

Harris Bed Bug Killer

Every bedbug, everytime

This highly-effective spray will get rid of even the most difficult bedbugs, so you can get back to your clean covers in no time.

Best Overall

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If you have a tough bed bug problem to stop, this spray is definitely worth a try. It’s designed to kill every single bed bug, including those that are resistant to pyrethroid (the chemical compound that many pest control sprays use as their main ingredient).

This spray works by stopping bedbugs in direct contact, but it also kills the ones that continue to come as days and weeks go on. It can be effective for up to 16 weeks after it’s applied, ensuring no single bug will make it out alive.

Pros:

• This spray is odorless and won’t hurt the fabrics on your bed or floor
• It’s EPA-registered as safe for use around both people and pets
• It comes in a large bottle with a hosed nozzle for easy spraying

Cons:

• This has a high price point, but its effectiveness is worth it to many

Eco Defense Bed Bug Spray

The safer spray

Worried about kids crawling around chemicals? This bed bug killer is natural and non-toxic for your family's protection.

Best Non-Toxic Spray

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This bed bug spray is perfect for anyone who wants to tackle the problem naturally. It’s made with organic ingredients and it’s completely non-toxic for both child and pet safety, too.

This concoction comes in a 16oz spray bottle for easy application anywhere in your home. It kills bed bugs on contact, destroying their eggs as well so no more can hatch in the future. Because of this, you’ll notice the results right away after you spray.

Pros:

• This doesn’t leave fumes or chemicals behind
• It’s safe for use on fabrics in your home

Cons:

• This bed bug spray isn’t able to continue killing the pests for weeks after application, but you can always apply it again if your problem persists 

Proof Bed Bug and Dust Mite Killer

Plant power

Let the incredible power of plants get rid of those little pests with this extra-strong, organic bed bug spray.

Best Plant-Based Spray

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Plants have tons of extremely useful characteristics and, with this spray, killing bed bugs is one of them. The mixture is entirely plant-based, organic, and natural, and non-toxic, ensuring it’s safe for use all over your family’s home.

This spray comes in an easy-to-use 16oz bottle. It kills bed bugs on contact and it takes care of dust mites, too, giving you double the benefits for your dollar. The mixture also kills these creatures for two weeks after application, helping you take care of the entire problem on your first try.

Pros:

• This bed bug spray is safe for use on the fabrics in your home
• It’s sold at a fairly affordable price compared to other versions available today
• It’s an excellent product for bringing fewer chemicals into your home 

Cons:

• The lack of strong ingredients makes this not last quite as long as other sprays, but it can still take care of most bed bug infestations right away

Ortho Home Defense Bed Bug, Flea, and Tick Killer

Bugs be gone

This spray kills not only bed bugs, but fleas and ticks as well, ensuring your home will be insect-free after application.

Best Multi-Purpose

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This bed bug spray is extra strong and it’s designed to kill tons of other unwanted critters, too. Specifically, it can get rid of bed bugs in both adult and egg form, as well as fleas and ticks, leaving your home pest-free.

This spray comes in a large bottle with a spray hose attached for easy use. It kills all bed bugs, including those that are pyrethroid-resistant. Plus, it’s designed to be safe in all areas of your home.

Pros:

• This concoction can be purchased in aerosol cans, powders, and more, in case the large spray jug isn’t your style
• It’s extremely affordable considering the large amount of spray you receive

Cons:

• This is made with stronger chemicals, which some users prefer to avoid

Eagle Watch Travel Bed Bug Spray

Portable protection

Keep creepy crawlies away at hotels and other shared sleeping spots with this travel-sized bed bug spray.

Best For Travel

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Bed bugs obviously aren’t welcome in your home, but you also don’t want to encounter them while you’re out and about. This travel spray is perfect for ensuring you won’t have to deal with these pests at hotels or in other public sleeping arrangements.

This bed bug spray comes in a small, just over 3oz bottle, so it can easily be thrown in a travel bag and brought with you wherever you go. It’s great for having on backup just in case you happen to run into a bed bug issue while you’re away.

Pros:

• This spray is designed to be safe, non-toxic, and eco-friendly, so you can sleep on the surface after application
• It kills on contact, producing the immediate effect you need while you’re in a new space
• Larger bottles are available if you’d like to have the same ingredients for at-home use

Cons:

• This is a small bottle, so it may need to be replaced after one or two uses

Frequently Asked Questions

What does it mean when bed bugs are pyrethroid-resistant?

Pyrethroids are a common chemical used in insecticides. Sometimes, pests learn to live through this spray, making many bed bug products ineffective. If you’ve got a long-lasting bed bug problem or have had a specific spray fail in the past, a version designed for pyrethroid-resistant critters may be a good product to try next.

Which chemicals are safest for use around kids?

For safety and peace of mind with little ones, you may want to choose one of the more natural, non-toxic sprays on the list above.